Intake of selected minerals and risk of premenstrual syndrome.
Chocano-Bedoya PO1, Manson JE, Hankinson SE, Johnson SR, Chasan-Taber L, Ronnenberg AG, Bigelow C, Bertone-Johnson ER.
1Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Abstract
Iron,
potassium, zinc, and other minerals might impact the development of
premenstrual syndrome (PMS) through multiple mechanisms, but few studies
have evaluated these relations. We conducted a case-control study
nested within the prospective Nurses' Health Study II (1991-2001).
Participants were free from PMS at baseline. After 10 years, 1,057 women
were confirmed as PMS cases and 1,968 as controls. Mineral intake was
assessed using food frequency questionnaires completed in 1991, 1995,
and 1999. After adjustment for calcium intake and other factors, women
in the highest quintile of nonheme iron intake had a relative risk of
PMS of 0.64 (95% confidence interval (CI): 0.44, 0.92; P for trend =
0.04) compared with women in the lowest quintile. Women in the highest
quintile of potassium intake had a relative risk of 1.46 (95% CI: 0.99,
2.15; P for trend = 0.04) compared with women in the lowest quintile.
High intake of zinc from supplements was marginally associated with PMS
(for intake of ≥25 mg/day vs. none, relative risk = 0.69, 95% CI: 0.46,
1.02; P for trend = 0.05). Intakes of sodium, magnesium, and manganese
were unrelated to PMS risk. These findings suggest that dietary minerals
may be useful in preventing PMS. Additional studies are needed to
confirm these relations.
KEYWORDS:
dietary iron; minerals; premenstrual syndromeAm J Epidemiol. 2013 May 15;177(10):1118-27. doi: 10.1093/aje/kws363. Epub 2013 Feb 26.
http://aje.oxfordjournals.org/content/177/10/1118.long
Md. PhD. Patricia Chocano. Ex miembro del GII.
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