Dermatología e Inmunología

Mastocitos y basófilos y sus nuevas funciones en inmunología

 Julio E Valdivia-Silva 

1Chemokines Biology Research Laboratory, Instituto de Investigaciones Biomédicas, UNAM, México D.F., México.

ABSTRACT 

Mast cells and basophils have demonstrated to have both beneficial and detrimental functions for the immune system. Additionally to their classic role in pro-inflammatory responses to allergens, they are also involved directly in immunity against different pathogens. Because there are few animals models developed to investigate these cells in vivo, their functions during health and disease remain poorly understood. This review gives a short glance in the development and functional status of mast cells and basophils focusing on immunology concepts necessary to get a major understanding of the mechanisms of disease in different pathological states. 

DERMATOL PERU 2012; VOL 23

http://sisbib.unmsm.edu.pe/bvrevistas/dermatologia/v23_n2/pdf/a04v23n2.pdf

Md PhD Julio Valdivia Silva. Fundador del GII