Vitamin D and tuberculosis.
1Department of Nutrition, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Abstract
Tuberculosis
is highly prevalent worldwide, accounting for nearly two million deaths
annually. Vitamin D influences the immune response to tuberculosis, and
vitamin D deficiency has been associated with increased tuberculosis
risk in different populations. Genetic variability may influence host
susceptibility to developing active tuberculosis and treatment response.
Studies examining the association between genetic polymorphisms,
particularly the gene coding for the vitamin D receptor (VDR), and TB
susceptibility and treatment response are inconclusive. However,
sufficient evidence is available to warrant larger epidemiologic studies
that should aim to identify possible interactions between VDR
polymorphisms and vitamin D status.
Nutr Rev. 2009 May;67(5):289-93. doi: 10.1111/j.1753-4887.2009.00195.x.
http://nutritionreviews.oxfordjournals.org/content/67/5/289.long
Md. PhD. Patricia Chocano. Ex miembro del GII.
